Drug manufacturers that have profited for years from the rising demand for prescriptions painkillers in the U.S. are coming under greater scrutiny than ever as a bipartisan group of states begin probing the industry’s role in a devastating opioids epidemic.

Massachusetts Attorney General Maura Healey, who is helping to lead the effort, said on Thursday that the coalition is issuing subpoenas for documents and testimony, but she didn’t name any of the companies being looked into. Her counterparts in New York, Connecticut and Vermont are also part of the group.

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