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Health stock winners and losers in 2017

In a testament to how good a year 2017 was for some health-care stocks, four health companies are among the S&P 500s 20 biggest gains, three of them businesses with less than $3 billion in annual revenue.

By Cecile Daurat | Updated on December 29, 2017

In a year when the Standard & Poor’s 500 Index reached new records on a regular basis, the best-performing stock is a relatively small provider of dental products.

Align Technology Inc., the maker of the clear teeth-straightener Invisalign, is on pace to become the index’s winner this year with a 136 percent increase as of Dec. 28. With estimated revenue of $1.49 billion in 2017, the San Jose, California-based company’s sales have almost doubled in just three years as popularity of its smile-correcting products grew. It remains tiny within the S&P 500, where average annual sales are $22 billion.

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